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KMID : 0861220010030020156
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Journal of the Korean Society Clinical Neurophysiology
2001 Volume.3 No. 2 p.156 ~ p.159
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Serial Electrophysiological Studies in Miller Fisher Syndrome
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Jun Dong-Chul
Park Choon-Gang
Lee Kyu-Yong
Lee Yong-Joo
Kim Ju-Han
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Abstract
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Miller Fisher syndrome(MFS) has been the focus of conflicting opinions regarding the peripheral versus the central nature of the site of major neural injury. We present out electrophysiological findings in one case of MFS to help clarify the patterns of peripheral nerve injury in this syndrome. A 45-year-old man visited our hospital due to sudden diplopia. Initial examination revealed internuclear opthalmoplegia. The next day, his symptoms rapidly aggravated to complete external opthalmoplegia, ataxia, and areflexia with hand and foot numbness. Serial electrophysiological studies were performed. The results of brainstem evoked potential(BAEP) and blink reflex were normal in the serial studies. Motor and sensory nerve conduction study(NCS) were normal findings in second hospital day, but ulnar sensory nerve shows no sensory nerve action potential(SNAP) and sural sensory conduction velocity was delayed in 7th hospital day. Our patient’s clinical presentation began to improve on 15th hospital day, and his electrophysiologic study showed improvement on 29th hospital day. We believe that all the manifestations of MFS can be explained by the involvement of peripheral nerves without brainstem or cerebellar lesion with the serial electrophysiological studies.
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KEYWORD
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Miller Fisher syndrome, Electrophysiologic study
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